siRNA, Anti-SUPT4H1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21476WQ-2OMe)

The product SIRGT21476WQ-2OMe is a type of small interfering RNA (siRNA) that targets SUPT4H1 gene and regulates the expression of gene. The siRNA interferes with the expression of SUPT4H1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003168.2
Alternative Names SPT4; SPT4H; SUPT4H; Supt4a
Related Diseases Amyotrophic Lateral Sclerosis
Purification HPLC
Target Gene
Gene ID 6827
Uniprot ID P63272
Sub Cat Target Species Modification Scale  
SIRGT22476WQ-2F SUPT4H1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23476WQ-2MOE SUPT4H1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24476WQ-LNA SUPT4H1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21476WQ-RB SUPT4H1 Human Ribo-modified Inquiry
SIRGT22476WQ-BB SUPT4H1 Human Backbone-modified Inquiry

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