siRNA, Anti-TBR1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT36022WQ-2OMe)

The product SIRGT36022WQ-2OMe is a type of small interfering RNA (siRNA) that targets TBR1 gene and regulates the expression of gene. The siRNA interferes with the expression of TBR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006593.3
Alternative Names TBR-1; TES-56
Related Diseases Pervasive Developmental Disorder
Purification HPLC
Target Gene
Gene ID 10716
Uniprot ID Q16650
Sub Cat Target Species Modification Scale  
SIRGT37022WQ-2F TBR1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT38022WQ-2MOE TBR1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT39022WQ-LNA TBR1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT36022WQ-RB TBR1 Human Ribo-modified Inquiry
SIRGT37022WQ-BB TBR1 Human Backbone-modified Inquiry

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