siRNA, Anti-TDG, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21578WQ-2OMe)

The product SIRGT21578WQ-2OMe is a type of small interfering RNA (siRNA) that targets TDG gene and regulates the expression of gene. The siRNA interferes with the expression of TDG gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003211.4
Alternative Names hTDG
Related Diseases Toxic Diffuse Goiter, Miles-Carpenter Syndrome
Purification HPLC
Target Gene
Gene ID 6996
Uniprot ID Q13569
Sub Cat Target Species Modification Scale  
SIRGT22578WQ-2F TDG Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23578WQ-2MOE TDG Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24578WQ-LNA TDG Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21578WQ-RB TDG Human Ribo-modified Inquiry
SIRGT22578WQ-BB TDG Human Backbone-modified Inquiry

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