siRNA, Anti-TECTA, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21586WQ-2OMe)

The product SIRGT21586WQ-2OMe is a type of small interfering RNA (siRNA) that targets TECTA gene and regulates the expression of gene. The siRNA interferes with the expression of TECTA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005422.2
Alternative Names DFNA12; DFNA8; DFNB21
Related Diseases Autosomal dominant nonsyndromic hearing impairment
Purification HPLC
Target Gene
Gene ID 7007
Uniprot ID O75443
Sub Cat Target Species Modification Scale  
SIRGT22586WQ-2F TECTA Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23586WQ-2MOE TECTA Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24586WQ-LNA TECTA Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21586WQ-RB TECTA Human Ribo-modified Inquiry
SIRGT22586WQ-BB TECTA Human Backbone-modified Inquiry

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