siRNA, Anti-THG1L, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT41436WQ-2OMe)

The product SIRGT41436WQ-2OMe is a type of small interfering RNA (siRNA) that targets THG1L gene and regulates the expression of gene. The siRNA interferes with the expression of THG1L gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001317824.1
Alternative Names ICF45; IHG-1; hTHG1
Related Diseases Renal Fibrosis
Purification HPLC
Target Gene
Gene ID 54974
Uniprot ID Q9NWX6
Sub Cat Target Species Modification Scale  
SIRGT42436WQ-2F THG1L Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43436WQ-2MOE THG1L Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44436WQ-LNA THG1L Human Locked Nucleic Acid (LNA) Inquiry

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