siRNA, Anti-THOP1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21636WQ-2OMe)

The product SIRGT21636WQ-2OMe is a type of small interfering RNA (siRNA) that targets THOP1 gene and regulates the expression of gene. The siRNA interferes with the expression of THOP1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003249.4
Alternative Names EP24.15; MEPD_HUMAN; MP78; TOP
Related Diseases Trypanosomiasis
Purification HPLC
Target Gene
Gene ID 7064
Uniprot ID P52888
Sub Cat Target Species Modification Scale  
SIRGT22636WQ-2F THOP1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23636WQ-2MOE THOP1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24636WQ-LNA THOP1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21636WQ-RB THOP1 Human Ribo-modified Inquiry
SIRGT22636WQ-BB THOP1 Human Backbone-modified Inquiry

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