siRNA, Anti-TMCO1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT41188WQ-2OMe)

The product SIRGT41188WQ-2OMe is a type of small interfering RNA (siRNA) that targets TMCO1 gene and regulates the expression of gene. The siRNA interferes with the expression of TMCO1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001256164.1
Alternative Names HP10122; PCIA3; PNAS-136; TMCC4
Related Diseases Pulmonic Stenosis
Purification HPLC
Target Gene
Gene ID 54499
Uniprot ID Q9UM00
Sub Cat Target Species Modification Scale  
SIRGT42188WQ-2F TMCO1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43188WQ-2MOE TMCO1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT41188WQ-RB TMCO1 Human Ribo-modified Inquiry
SIRGT42188WQ-BB TMCO1 Human Backbone-modified Inquiry

Related Products