siRNA, Anti-TMEM140, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41664WQ-2OMe)

The product SIRGT41664WQ-2OMe is a type of small interfering RNA (siRNA) that targets TMEM140 gene and regulates the expression of gene. The siRNA interferes with the expression of TMEM140 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_018295.4
Related Diseases Gliomas
Purification HPLC
Target Gene
Gene ID 55281
Uniprot ID Q9NV12
Sub Cat Target Species Modification Scale  
SIRGT42664WQ-2F TMEM140 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43664WQ-2MOE TMEM140 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44664WQ-LNA TMEM140 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41664WQ-RB TMEM140 Human Ribo-modified Inquiry
SIRGT42664WQ-BB TMEM140 Human Backbone-modified Inquiry

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