siRNA, Anti-TNR, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21702WQ-2OMe)

The product SIRGT21702WQ-2OMe is a type of small interfering RNA (siRNA) that targets TNR gene and regulates the expression of gene. The siRNA interferes with the expression of TNR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001328635.1; NM_003285.2
Alternative Names TN-R
Related Diseases Osteochondritis Dissecans
Purification HPLC
Target Gene
Gene ID 7143
Uniprot ID Q92752
Sub Cat Target Species Modification Scale  
SIRGT22702WQ-2F TNR Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23702WQ-2MOE TNR Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24702WQ-LNA TNR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21702WQ-RB TNR Human Ribo-modified Inquiry
SIRGT22702WQ-BB TNR Human Backbone-modified Inquiry

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