siRNA, Anti-TSPAN7, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21670WQ-2OMe)
The product SIRGT21670WQ-2OMe is a type of small interfering RNA (siRNA) that targets TSPAN7 gene and regulates the expression of gene. The siRNA interferes with the expression of TSPAN7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_004615.3 |
| Alternative Names | A15; CCG-B7; CD231; DXS1692E; MRX58; MXS1; TALLA-1; TM4SF2; TM4SF2b |
| Related Diseases | X-linked cognitive disability |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT22670WQ-2F | TSPAN7 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT23670WQ-2MOE | TSPAN7 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT24670WQ-LNA | TSPAN7 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT21670WQ-RB | TSPAN7 | Human | Ribo-modified | ||
| SIRGT22670WQ-BB | TSPAN7 | Human | Backbone-modified |