siRNA, Anti-TUBB2A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21773WQ-2OMe)

The product SIRGT21773WQ-2OMe is a type of small interfering RNA (siRNA) that targets TUBB2A gene and regulates the expression of gene. The siRNA interferes with the expression of TUBB2A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001069.2; NM_001310315.1
Alternative Names CDCBM5; TUBB; TUBB2
Related Diseases Cortical Dysplasia
Purification HPLC
Target Gene
Gene ID 7280
Uniprot ID Q13885
Sub Cat Target Species Modification Scale  
SIRGT22773WQ-2F TUBB2A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23773WQ-2MOE TUBB2A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24773WQ-LNA TUBB2A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21773WQ-RB TUBB2A Human Ribo-modified Inquiry
SIRGT22773WQ-BB TUBB2A Human Backbone-modified Inquiry

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