siRNA, Anti-TUFT1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21776WQ-2OMe)

The product SIRGT21776WQ-2OMe is a type of small interfering RNA (siRNA) that targets TUFT1 gene and regulates the expression of gene. The siRNA interferes with the expression of TUFT1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001126337.1; NM_001301317.1; NM_020127.2
Related Diseases Amelogenesis Imperfecta, Dental Caries
Purification HPLC
Target Gene
Gene ID 7286
Uniprot ID Q9NNX1
Sub Cat Target Species Modification Scale  
SIRGT22776WQ-2F TUFT1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23776WQ-2MOE TUFT1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24776WQ-LNA TUFT1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21776WQ-RB TUFT1 Human Ribo-modified Inquiry
SIRGT22776WQ-BB TUFT1 Human Backbone-modified Inquiry

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