siRNA, Anti-TYMS, 2'-F/2'-OMe/2'-MOE/Ribo-modified(CAT#: SIRGT21788WQ-2OMe)

The product SIRGT21788WQ-2OMe is a type of small interfering RNA (siRNA) that targets TYMS gene and regulates the expression of gene. The siRNA interferes with the expression of TYMS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001071.2; NM_001354867.1; NM_001354868.1
Alternative Names HST422; TMS; TS
Related Diseases Dihydropyrimidine Dehydrogenase Deficiency
Purification HPLC
Target Gene
Gene ID 7298
Uniprot ID P04818
Sub Cat Target Species Modification Scale  
SIRGT22788WQ-2F TYMS Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23788WQ-2MOE TYMS Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT21788WQ-RB TYMS Human Ribo-modified Inquiry

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