siRNA, Anti-UBE2I, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21808WQ-2OMe)

The product SIRGT21808WQ-2OMe is a type of small interfering RNA (siRNA) that targets UBE2I gene and regulates the expression of gene. The siRNA interferes with the expression of UBE2I gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003345.4; NM_194259.2; NM_194260.2; NM_194261.2
Alternative Names C358B7.1; P18; UBC9
Related Diseases Microphthalmia
Purification HPLC
Target Gene
Gene ID 7329
Uniprot ID P63279
Sub Cat Target Species Modification Scale  
SIRGT22808WQ-2F UBE2I Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23808WQ-2MOE UBE2I Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24808WQ-LNA UBE2I Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21808WQ-RB UBE2I Human Ribo-modified Inquiry
SIRGT22808WQ-BB UBE2I Human Backbone-modified Inquiry

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