siRNA, Anti-UCN, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21818WQ-2OMe)

The product SIRGT21818WQ-2OMe is a type of small interfering RNA (siRNA) that targets UCN gene and regulates the expression of gene. The siRNA interferes with the expression of UCN gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003353.3
Alternative Names UI; UROC
Related Diseases Ulcerative Colitis, Colitis
Purification HPLC
Target Gene
Gene ID 7349
Uniprot ID P55089
Sub Cat Target Species Modification Scale  
SIRGT22818WQ-2F UCN Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23818WQ-2MOE UCN Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24818WQ-LNA UCN Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21818WQ-RB UCN Human Ribo-modified Inquiry
SIRGT22818WQ-BB UCN Human Backbone-modified Inquiry

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