siRNA, Anti-UGT1A5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41235WQ-2OMe)

The product SIRGT41235WQ-2OMe is a type of small interfering RNA (siRNA) that targets UGT1A5 gene and regulates the expression of gene. The siRNA interferes with the expression of UGT1A5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_019078.1
Alternative Names UDPGT; UDPGT 1-5; UGT1E
Related Diseases Gilbert Syndrome
Purification HPLC
Target Gene
Gene ID 54579
Uniprot ID P35504
Sub Cat Target Species Modification Scale  
SIRGT42235WQ-2F UGT1A5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43235WQ-2MOE UGT1A5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44235WQ-LNA UGT1A5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41235WQ-RB UGT1A5 Human Ribo-modified Inquiry
SIRGT42235WQ-BB UGT1A5 Human Backbone-modified Inquiry

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