siRNA, Anti-UGT2B7, 2'-F/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT22829WQ-2F)
The product SIRGT22829WQ-2F is a type of small interfering RNA (siRNA) that targets UGT2B7 gene and regulates the expression of gene. The siRNA interferes with the expression of UGT2B7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001074.3; NM_001330719.1; NM_001349568.1 |
| Alternative Names | UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTh-2; UGT2B9 |
| Related Diseases | Neonatal Abstinence Syndrome |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT23829WQ-2MOE | UGT2B7 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT24829WQ-LNA | UGT2B7 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT21829WQ-RB | UGT2B7 | Human | Ribo-modified | ||
| SIRGT22829WQ-BB | UGT2B7 | Human | Backbone-modified |
