siRNA, Anti-UNC5C, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26450WQ-2OMe)

The product SIRGT26450WQ-2OMe is a type of small interfering RNA (siRNA) that targets UNC5C gene and regulates the expression of gene. The siRNA interferes with the expression of UNC5C gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003728.3
Alternative Names UNC5H3
Related Diseases Alzheimer Disease
Purification HPLC
Target Gene
Gene ID 8633
Uniprot ID O95185
Sub Cat Target Species Modification Scale  
SIRGT27450WQ-2F UNC5C Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28450WQ-2MOE UNC5C Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29450WQ-LNA UNC5C Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26450WQ-RB UNC5C Human Ribo-modified Inquiry
SIRGT27450WQ-BB UNC5C Human Backbone-modified Inquiry

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