siRNA, Anti-UQCRC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21845WQ-2OMe)

The product SIRGT21845WQ-2OMe is a type of small interfering RNA (siRNA) that targets UQCRC1 gene and regulates the expression of gene. The siRNA interferes with the expression of UQCRC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003365.2
Alternative Names D3S3191; QCR1; UQCR1
Related Diseases Leukodystrophy, Hypomyelinating
Purification HPLC
Target Gene
Gene ID 7384
Uniprot ID P31930
Sub Cat Target Species Modification Scale  
SIRGT22845WQ-2F UQCRC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23845WQ-2MOE UQCRC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24845WQ-LNA UQCRC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21845WQ-RB UQCRC1 Human Ribo-modified Inquiry
SIRGT22845WQ-BB UQCRC1 Human Backbone-modified Inquiry

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