siRNA, Anti-UQCRFS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21847WQ-2OMe)

The product SIRGT21847WQ-2OMe is a type of small interfering RNA (siRNA) that targets UQCRFS1 gene and regulates the expression of gene. The siRNA interferes with the expression of UQCRFS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006003.2
Alternative Names RIP1; RIS1; RISP; UQCR5
Related Diseases Lactic Acidosis, Propionic Acidemia
Purification HPLC
Target Gene
Gene ID 7386
Uniprot ID P47985
Sub Cat Target Species Modification Scale  
SIRGT22847WQ-2F UQCRFS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23847WQ-2MOE UQCRFS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24847WQ-LNA UQCRFS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21847WQ-RB UQCRFS1 Human Ribo-modified Inquiry
SIRGT22847WQ-BB UQCRFS1 Human Backbone-modified Inquiry

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