siRNA, Anti-URM1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46654WQ-2OMe)

The product SIRGT46654WQ-2OMe is a type of small interfering RNA (siRNA) that targets URM1 gene and regulates the expression of gene. The siRNA interferes with the expression of URM1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001135947.2
Alternative Names C9orf74
Related Diseases Benign Epilepsy With Centrotemporal Spikes
Purification HPLC
Target Gene
Gene ID 81605
Uniprot ID Q9BTM9
Sub Cat Target Species Modification Scale  
SIRGT47654WQ-2F URM1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48654WQ-2MOE URM1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49654WQ-LNA URM1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46654WQ-RB URM1 Human Ribo-modified Inquiry
SIRGT47654WQ-BB URM1 Human Backbone-modified Inquiry

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