siRNA, Anti-VNN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT26637WQ-2OMe)

The product SIRGT26637WQ-2OMe is a type of small interfering RNA (siRNA) that targets VNN1 gene and regulates the expression of gene. The siRNA interferes with the expression of VNN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004666.2
Alternative Names HDLCQ8; Tiff66
Related Diseases Obstructive Nephropathy, Malaria
Purification HPLC
Target Gene
Gene ID 8876
Uniprot ID O95497
Sub Cat Target Species Modification Scale  
SIRGT27637WQ-2F VNN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT28637WQ-2MOE VNN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT29637WQ-LNA VNN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26637WQ-RB VNN1 Human Ribo-modified Inquiry
SIRGT27637WQ-BB VNN1 Human Backbone-modified Inquiry

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