siRNA, Anti-VPS25, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46906WQ-2OMe)

The product SIRGT46906WQ-2OMe is a type of small interfering RNA (siRNA) that targets VPS25 gene and regulates the expression of gene. The siRNA interferes with the expression of VPS25 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032353.3
Alternative Names DERP9; EAP20; FAP20
Related Diseases Rigid Spine Muscular Dystrophy
Purification HPLC
Target Gene
Gene ID 84313
Uniprot ID Q9BRG1
Sub Cat Target Species Modification Scale  
SIRGT47906WQ-2F VPS25 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48906WQ-2MOE VPS25 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49906WQ-LNA VPS25 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46906WQ-RB VPS25 Human Ribo-modified Inquiry
SIRGT47906WQ-BB VPS25 Human Backbone-modified Inquiry

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