siRNA, Anti-VPS51, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT01494WQ-2OMe)

The product SIRGT01494WQ-2OMe is a type of small interfering RNA (siRNA) that targets VPS51 gene and regulates the expression of gene. The siRNA interferes with the expression of VPS51 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_013265.3
Alternative Names ANG2; ANG3; C11orf2; C11orf3; FFR
Related Diseases Pontocerebellar Hypoplasia
Purification HPLC
Target Gene
Gene ID 738
Uniprot ID Q9UID3
Sub Cat Target Species Modification Scale  
SIRGT02494WQ-2F VPS51 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT03494WQ-2MOE VPS51 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT04494WQ-LNA VPS51 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT01494WQ-RB VPS51 Human Ribo-modified Inquiry
SIRGT02494WQ-BB VPS51 Human Backbone-modified Inquiry

Related Products