siRNA, Anti-VWF, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21891WQ-2OMe)

The product SIRGT21891WQ-2OMe is a type of small interfering RNA (siRNA) that targets VWF gene and regulates the expression of gene. The siRNA interferes with the expression of VWF gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000552.4
Alternative Names F8VWF; VWD
Related Diseases von Willebrand disease
Purification HPLC
Target Gene
Gene ID 7450
Uniprot ID P04275
Sub Cat Target Species Modification Scale  
SIRGT22891WQ-2F VWF Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23891WQ-2MOE VWF Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24891WQ-LNA VWF Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21891WQ-RB VWF Human Ribo-modified Inquiry
SIRGT22891WQ-BB VWF Human Backbone-modified Inquiry

Related Products