siRNA, Anti-WNT1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21904WQ-2OMe)

The product SIRGT21904WQ-2OMe is a type of small interfering RNA (siRNA) that targets WNT1 gene and regulates the expression of gene. The siRNA interferes with the expression of WNT1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005430.3
Alternative Names BMND16; INT1; OI15
Related Diseases Osteogenesis Imperfecta, Type Xv
Purification HPLC
Target Gene
Gene ID 7471
Uniprot ID P04628
Sub Cat Target Species Modification Scale  
SIRGT22904WQ-2F WNT1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23904WQ-2MOE WNT1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24904WQ-LNA WNT1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21904WQ-RB WNT1 Human Ribo-modified Inquiry
SIRGT22904WQ-BB WNT1 Human Backbone-modified Inquiry

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