siRNA, Anti-WNT10B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21913WQ-2OMe)

The product SIRGT21913WQ-2OMe is a type of small interfering RNA (siRNA) that targets WNT10B gene and regulates the expression of gene. The siRNA interferes with the expression of WNT10B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003394.3
Alternative Names SHFM6; STHAG8; WNT-12
Related Diseases Split-Hand/Foot Malformation
Purification HPLC
Target Gene
Gene ID 7480
Uniprot ID O00744
Sub Cat Target Species Modification Scale  
SIRGT22913WQ-2F WNT10B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23913WQ-2MOE WNT10B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24913WQ-LNA WNT10B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21913WQ-RB WNT10B Human Ribo-modified Inquiry
SIRGT22913WQ-BB WNT10B Human Backbone-modified Inquiry

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