siRNA, Anti-WNT11, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21914WQ-2OMe)

The product SIRGT21914WQ-2OMe is a type of small interfering RNA (siRNA) that targets WNT11 gene and regulates the expression of gene. The siRNA interferes with the expression of WNT11 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004626.2
Alternative Names HWNT11
Related Diseases High Bone Mass Syndrome
Purification HPLC
Target Gene
Gene ID 7481
Uniprot ID O96014
Sub Cat Target Species Modification Scale  
SIRGT22914WQ-2F WNT11 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23914WQ-2MOE WNT11 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24914WQ-LNA WNT11 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21914WQ-RB WNT11 Human Ribo-modified Inquiry
SIRGT22914WQ-BB WNT11 Human Backbone-modified Inquiry

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