siRNA, Anti-WNT7A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21909WQ-2OMe)

The product SIRGT21909WQ-2OMe is a type of small interfering RNA (siRNA) that targets WNT7A gene and regulates the expression of gene. The siRNA interferes with the expression of WNT7A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004625.3
Related Diseases Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes
Purification HPLC
Target Gene
Gene ID 7476
Uniprot ID O00755
Sub Cat Target Species Modification Scale  
SIRGT22909WQ-2F WNT7A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23909WQ-2MOE WNT7A Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24909WQ-LNA WNT7A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21909WQ-RB WNT7A Human Ribo-modified Inquiry
SIRGT22909WQ-BB WNT7A Human Backbone-modified Inquiry

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