siRNA, Anti-WNT7B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21910WQ-2OMe)

The product SIRGT21910WQ-2OMe is a type of small interfering RNA (siRNA) that targets WNT7B gene and regulates the expression of gene. The siRNA interferes with the expression of WNT7B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_058238.2
Related Diseases Persistent Hyperplastic Primary Vitreous
Purification HPLC
Target Gene
Gene ID 7477
Uniprot ID P56706
Sub Cat Target Species Modification Scale  
SIRGT22910WQ-2F WNT7B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23910WQ-2MOE WNT7B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24910WQ-LNA WNT7B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21910WQ-RB WNT7B Human Ribo-modified Inquiry
SIRGT22910WQ-BB WNT7B Human Backbone-modified Inquiry

Related Products