siRNA, Anti-XRCC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21930WQ-2OMe)

The product SIRGT21930WQ-2OMe is a type of small interfering RNA (siRNA) that targets XRCC1 gene and regulates the expression of gene. The siRNA interferes with the expression of XRCC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006297.2
Alternative Names RCC; SCAR26
Related Diseases Gastric Cardia Carcinoma
Purification HPLC
Target Gene
Gene ID 7515
Uniprot ID P18887
Sub Cat Target Species Modification Scale  
SIRGT22930WQ-2F XRCC1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23930WQ-2MOE XRCC1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24930WQ-LNA XRCC1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21930WQ-RB XRCC1 Human Ribo-modified Inquiry
SIRGT22930WQ-BB XRCC1 Human Backbone-modified Inquiry

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