siRNA, Anti-YWHAH, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21940WQ-2OMe)

The product SIRGT21940WQ-2OMe is a type of small interfering RNA (siRNA) that targets YWHAH gene and regulates the expression of gene. The siRNA interferes with the expression of YWHAH gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003405.3
Alternative Names YWHA1
Related Diseases Early-onset schizophrenia and psychotic bipolar disorder
Purification HPLC
Target Gene
Gene ID 7533
Uniprot ID Q04917
Sub Cat Target Species Modification Scale  
SIRGT22940WQ-2F YWHAH Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23940WQ-2MOE YWHAH Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24940WQ-LNA YWHAH Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21940WQ-RB YWHAH Human Ribo-modified Inquiry
SIRGT22940WQ-BB YWHAH Human Backbone-modified Inquiry

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