siRNA, Anti-ZEB2, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT31335WQ-2OMe)

The product SIRGT31335WQ-2OMe is a type of small interfering RNA (siRNA) that targets ZEB2 gene and regulates the expression of gene. The siRNA interferes with the expression of ZEB2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001171653.1; NM_014795.3
Alternative Names HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
Related Diseases Hirschsprung disease/Mowat-Wilson syndrome
Purification HPLC
Target Gene
Gene ID 9839
Uniprot ID O60315
Sub Cat Target Species Modification Scale  
SIRGT32335WQ-2F ZEB2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT34335WQ-LNA ZEB2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31335WQ-RB ZEB2 Human Ribo-modified Inquiry
SIRGT32335WQ-BB ZEB2 Human Backbone-modified Inquiry

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