siRNA, Anti-ZYG11B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46145WQ-2OMe)

The product SIRGT46145WQ-2OMe is a type of small interfering RNA (siRNA) that targets ZYG11B gene and regulates the expression of gene. The siRNA interferes with the expression of ZYG11B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_024646.2
Alternative Names ZYG11
Related Diseases Hemophagocytic Lymphohistiocytosis
Purification HPLC
Target Gene
Gene ID 79699
Uniprot ID Q9C0D3
Sub Cat Target Species Modification Scale  
SIRGT47145WQ-2F ZYG11B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48145WQ-2MOE ZYG11B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49145WQ-LNA ZYG11B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46145WQ-RB ZYG11B Human Ribo-modified Inquiry
SIRGT47145WQ-BB ZYG11B Human Backbone-modified Inquiry

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