Human IL-12A Protein (Arg 23-Ser 219) [Fc] (VAng-1764Lsx)
Human IL-12A, Fc tag, is expressed in human 293 cells. (Uniprot ID: P29459)
Datasheet
Specifications
Source
HEK293 Cells.
Target
IL12A
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 92% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL12A (Interleukin 12A) is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. Diseases associated with IL12A include Primary Biliary Cholangitis and Atypical Autism.
Alternative Names
IL12A, CLMF, IL-12A, NFSK, NKSF1, P35
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