Human IL-37 Protein (Val 46-Asp 218) [His] (VAng-1823Lsx)

Human IL-37, His tag, Human protein expressed in human 293 cells. (Uniprot ID: AAH20637)

Specifications
Source
HEK293 Cells.
Target
IL37
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL37 (Interleukin 37) is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. Diseases associated with IL37 include Rheumatoid Arthritis and Eumycotic Mycetoma.
Alternative Names
IL1F7, IL37, FIL1Z, IL1H4, IL1RP1

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