Human NTB-A Protein (Gln 22-Met 226) [His] (VAng-2619Lsx)

Human NTB-A protein, His tag, was expressed in human 293 cells. (Uniprot ID: Q96DU3-1)

Datasheet

Specifications

Source

HEK293 cells

Target

SLAMF6

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

SLAMF6 (SLAM Family Member 6) is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Diseases associated with SLAMF6 include Lymphoproliferative Syndrome and Systemic Lupus Erythematosus.

Alternative Names

NTB-A, SLAMF6, Ly108, NK-T-B-antigen, CD352, KALI