shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(OR8H3-shRNA-Seq5)(CAT#: AdV-SI3000WQ)

This product is a OR8H3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR8H3 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR8H3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR8H3-shRNA-Seq5
Related Target/Protein OR8H3
Region CDS
TargetSeq CCTCTACACTACACAGTTATT
NCBI RefSeq XM_372391
Alternative Names OR11-172
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 390152
Uniprot ID Q8N146

Related Products