shRNA Adeno-associated Virus Serotype 2, pU6-(EWSR1-shRNA-Seq5)(CAT#: AAV-SI0038WQ)
This product is a EWSR1-shRNA encoding AAV, which is based on AAV-2 serotype. The EWSR1 gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The expression of EWSR1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | EWSR1-shRNA-Seq5 |
| Related Target/Protein | EWSR1 |
| Region | CDS |
| TargetSeq | GCAACAAAGCTATGGAACCTA |
| NCBI RefSeq | NM_005243 |
| Alternative Names | EWS; EWS-FLI1; bK984G1.4 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Ewing sarcoma as well as neuroectodermal tumors |
