siRNA, Anti-NEGR1, 2'-MOE/Backbone-modified(CAT#: SIRGT63615WQ-2MOE)

The product SIRGT63615WQ-2MOE is a type of small interfering RNA (siRNA) that targets NEGR1 gene and regulates the expression of gene. The siRNA interferes with the expression of NEGR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_173808.2
Alternative Names DMML2433; IGLON4; KILON; Ntra
Related Diseases Niemann-Pick Disease
Purification HPLC
Target Gene
Gene ID 257194
Uniprot ID Q7Z3B1
Sub Cat Target Species Modification Scale  
SIRGT62615WQ-BB NEGR1 Human Backbone-modified Inquiry

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