siRNA, Anti-NEGR1, 2'-OMe-modified(CAT#: SIRGT61615WQ-2OMe)

The product SIRGT61615WQ-2OMe is a type of small interfering RNA (siRNA) that targets NEGR1 gene and regulates the expression of gene. The siRNA interferes with the expression of NEGR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification 2ʹ-O-methyl (2'-OMe)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_173808.2
Alternative Names DMML2433; IGLON4; KILON; Ntra
Related Diseases Niemann-Pick Disease
Purification HPLC
Target Gene
Gene ID 257194
Uniprot ID Q7Z3B1

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