siRNA, Anti-CACNA1B, LNA-modified(CAT#: SIRGT04519WQ-LNA)

The product SIRGT04519WQ-LNA is a type of small interfering RNA (siRNA) that targets CACNA1B gene and regulates the expression of gene. The siRNA interferes with the expression of CACNA1B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000718.3; NM_001243812.1
Alternative Names BIII; CACNL1A5; CACNN; Cav2.2; DYT23
Related Diseases Neurodevelopmental Disorder With Seizures, Nonepileptic Hyperkinetic Movements
Purification HPLC
Target Gene
Gene ID 774
Uniprot ID Q00975

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