siRNA, Anti-HLA-DMB, 2'-F/2'-MOE/LNA-modified(CAT#: SIRGT12035WQ-2F)
The product SIRGT12035WQ-2F is a type of small interfering RNA (siRNA) that targets HLA-DMB gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-DMB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_002118.4 |
| Alternative Names | D6S221E; RING7 |
| Related Diseases | Rheumatoid Arthritis, Systemic Lupus Erythematosus |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT13035WQ-2MOE | HLA-DMB | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT14035WQ-LNA | HLA-DMB | Human | Locked Nucleic Acid (LNA) |
