siRNA, Anti-HLA-DMB, 2'-OMe-modified(CAT#: SIRGT11035WQ-2OMe)
The product SIRGT11035WQ-2OMe is a type of small interfering RNA (siRNA) that targets HLA-DMB gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-DMB gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-O-methyl (2'-OMe) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_002118.4 |
| Alternative Names | D6S221E; RING7 |
| Related Diseases | Rheumatoid Arthritis, Systemic Lupus Erythematosus |
| Purification | HPLC |