siRNA, Anti-NKX1-1, 2'-F-modified(CAT#: SIRGT42251WQ-2F)
The product SIRGT42251WQ-2F is a type of small interfering RNA (siRNA) that targets NKX1-1 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX1-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-deoxy-2ʹ-fluoro (2'-F) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001290079.1 |
| Alternative Names | HSPX153; NKX-1.1; SAX2 |
| Related Diseases | Orofaciodigital Syndrome Viii |
| Purification | HPLC |