siRNA, Anti-PKD1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT16396WQ-2OMe)

The product SIRGT16396WQ-2OMe is a type of small interfering RNA (siRNA) that targets PKD1 gene and regulates the expression of gene. The siRNA interferes with the expression of PKD1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000296.3; NM_001009944.2
Alternative Names PBP; PC1; Pc-1; TRPP1
Related Diseases Autosomal Dominant Polycystic Kidney Disease
Purification HPLC
Target Gene
Gene ID 5310
Uniprot ID P98161
Sub Cat Target Species Modification Scale  
SIRGT17396WQ-2F PKD1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT18396WQ-2MOE PKD1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT16396WQ-RB PKD1 Human Ribo-modified Inquiry
SIRGT17396WQ-BB PKD1 Human Backbone-modified Inquiry

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