siRNA, Anti-PKD1, LNA-modified(CAT#: SIRGT19396WQ-LNA)

The product SIRGT19396WQ-LNA is a type of small interfering RNA (siRNA) that targets PKD1 gene and regulates the expression of gene. The siRNA interferes with the expression of PKD1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
Modification Locked Nucleic Acid (LNA)
Scale 20/50/100/200 nmole
NCBI RefSeq NM_000296.3; NM_001009944.2
Alternative Names PBP; PC1; Pc-1; TRPP1
Related Diseases Autosomal Dominant Polycystic Kidney Disease
Purification HPLC
Target Gene
Gene ID 5310
Uniprot ID P98161

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