Targeted CD4 Ab-LNP

Cat. No.: TDLD-0825-LD65

Targeted CD4 Ab-LNP

Targeted CD4 Ab-LNP is a state-of-the-art antibody-functionalized lipid nanoparticle (LNP), designed for targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CD4 antibody, this LNP specifically recognizes and binds to the CD4 receptor expressed on the surface of helper T cells and other CD4⁺ cells, facilitating selective targeting and uptake into these specific cells. The LNPs can be supplied in an empty state, or pre-loaded with a variety of optimized mRNA molecules featuring capping and other modifications to enhance stability and expression. Our LNP is allows for the optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others, ensuring exceptional performance characterized by uniform particle size, high encapsulation efficiency, robust stability, and potent cellular uptake. Applications of Targeted CD4 Ab-LNP include investigating CD4 T cell function and serving as a versatile platform for delivering nucleic acid payloads specifically to CD4-expressing immune cells. Please note that this product is intended for research purposes only.