iRGD Pep-LNP

Cat. No.: TDLD-0825-LD80

iRGD Pep-LNP

iRGD Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the iRGD peptide, this LNP specifically recognizes integrin receptors, such as αvβ3 and αvβ5, on tumor vascular endothelial cells, enabling deeper penetration into the tumor microenvironment. Our LNP is prepared using DSPE-PEG-iRGD and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of iRGD Pep-LNP include research in targeted cancer therapy, overcoming drug resistance in solid tumors, and improving the efficacy of various therapeutic agents in the tumor microenvironment. Please note that this product is intended for research purposes only.