A7R Pep-LNP

Cat. No.: TDLD-0825-LD98

A7R Pep-LNP

A7R Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the A7R peptide, which binds with high affinity to the VEGFR2 (KDR) receptor on the surface of tumor neovasculature endothelial cells, this LNP facilitates the specific accumulation of the delivery system in tumor or pathological vascular regions, significantly enhancing drug concentration at the target site. Our LNP is prepared using DSPE-PEG-A7R and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of A7R Pep-LNP include targeted anti-angiogenic therapy, developing VEGFR2-specific imaging probes for tumor vasculature, studying tumor microenvironment and angiogenesis, and evaluating novel strategies for vascular-targeted drug delivery. Please note that this product is intended for research purposes only.